Oxydrene Elite

oxydrene elite

The Novex Biotech Oxydrene Elite label claims Oxydrene Elite is “clinically proven to increase VO2 max!!!”

Said to optimize systematic oxygen utilization, Oxydrene Elite supposedly maximizes physical performance and recovery.

Is there any science behind these claims? I took the liberty of finding out.

The Science

Below are all the ingredients in Novex Biotech Oxydrene Elite. I’ll tell you what works and what doesn’t.

Rhodiola Rosea is a popular medicinal plant in Russia, Scandinavia, and other countries. A study done on several foreign students shows taking rhodiola rosea improves physical fitness and mental fatigue. [1]

Cordyceps Sinensis is a fungus purported to improve oxidative capacity, increasing endurance during exercise. However, subjects taking 3 g daily for 5 weeks did not see any results. [2]

Coenzyme Q10 is a vitamin-like substance used to produce energy for cell growth and maintenance. When taken twice a day, coenzyme Q10 improves exercise performance. Studies show it increases maximal oxygen consumption and treadmill time to exhaustion. [3]

Schisandra Chinensis is used for increasing resistance to disease and stress, boosting energy, and improving exercise performance.[4] Animal studies show it increases time to exhaustion.[5] However, I was not able to find any human studies on schisandra chinensis.

Eleuthero Root Extract is a plant used to make medicine. Some say it enhances physical capacity. However, studies show it does not affect oxygen consumption, respiratory exchange, heart rate, or other exercise factors. [6]

L-Arginine Alphaketoglutarate is a naturally-produced chemical used for medicine. Arginine alphaketoglutarate supposedly peaks performance by reducing ammonia levels. However, the only studies showing arginine alphaketoglutarate reduces ammonia toxicity were performed on hemodialysis patients. While it was effective for them, there are no tests to show how arginine alphaketoglutarate works on healthy subjects. [7]

Ginkgo Biloba leaves contain flavonoids and terpenoids. However, studies show 24 weeks of supplementation, along with exercise, has no effect on physical capacity. [8]

Are the Ingredients Effective? In What Amounts?

Only rhodiola rosea and coenzyme Q10 are proven effective in humans.

Experts say correct dosage of rhodiola rosea depends on the user’s age, health, and several other conditions.[9] For coenzyme Q10, studies show 100 mg twice a day is needed. [3]

A Novex Biotech Oxydrene Elite serving contains a 7-ingredient, 255 mg blend. There may be enough of these ingredients to be effective, but it’s hard to tell.

Is Novex Biotech Oxydrene Elite Easy to Use?

This product is meant to be a pre-workout supplement. Simply take 2 capsules 1 hour before working out with a full glass of water.

Is There Anything to Be Worried About?

Novex Biotech Oxydrene Elite is an IOC- and WADA-banned substance. Take note before choosing it as a pre-workout supplement. This supplement is also not for users who are pregnant or under 18.

While Novex Biotech doesn’t list any side effects for Oxydrene, there are some side effects associated the ingredients.

These include nausea, loss of appetite, diarrhea, heartburn, itching, drowsiness, anxiety, dizziness, and constipation. [10] [11] [4] [12]

What Is the Difference Between Oxydrene and Oxydrene Elite?

Novex Biotech has another product on the market called Oxydrene. This product only contains rhodiola rosea root, eleuthero root, and schisandra chinensis. The differences between Oxydrene and Oxydrene Elite are the ingredients cordyceps sinensis, coenzyme Q10, L-arginine alphaketoglutarate, and ginkgo biloba.

Oxydrene is no longer listed on the Novex Biotech website, but is still carried by BodyBuilding.com, VitaminShoppe.com, LuckyVitamin.com, and VitaDigest.com.

To give you a feel for its effectiveness, customers on BodyBuilding.com gave Oxydrene a 6.9/10 rating.

Unfortunately, I’ve been unable to find reviews on Oxydrene Elite, which makes it hard to gauge effectiveness.


You can get Oxydrene Elite from various retailers, but the best prices I found were the following:

The Vitamin Shoppe – $44.99 with free shipping
Bodybuilding.com – $46.98
Vitacost – $53.49 with free shipping

Is Novex Biotech Oxydrene Elite Worth the Buy?

Novex Biotech Oxydrene Elite seems to be an improvement over the original Oxydrene, though I’m not sure about the ingredients’ effectiveness.

However, I always have confidence in a product carried by GNC. GNC is a trusted retailer and is confident in everything it sells.

While this product won’t work for everyone, it’s worth a shot if you are looking to move your workout to the next level.

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[1] A.A. Spasov, , G.K. Wikman, V.B. Mandrikov, I.A. Mironova, and V.V. Neumoin. "A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a." Phytomedicine (2000). Web. 19 July 2013. [2] Parcell, , Smith, Schulthies, Myrer, and Fellingham. "Cordyceps Sinensis (CordyMax Cs-4) supplementation does not improve endurance exercise performance." Int J Sport Nutr Exerc Metab. (2004). Web. 19 July 2013. [3] Cooke, Matthew, Mike Iosia, Thomas Buford, Brian Shelmadine, and Geoffrey Hudson. "Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals." Journal of the International Society of Sports Nutrition . Web. 19 July 2013. [4] "SCHISANDRA." WebMD.com. WebMD, n.d. Web. 19 July 2013. [5] Cao, Shehua, Huanping Shang, Weibing Wu, Jingrong Du, and Ramesh Putheti. "Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice." African Journal of Pharmacy and Pharmacology . Web. 19 July 2013. [6] Eschbach, , Webster, and Boyd. "The effect of siberian ginseng (Eleutherococcus senticosus) on substrate utilization and performance." . Web. 19 July 2013. [7] "ALPHA - KETOGLUTARATE." WebMD.com. WebMD, n.d. Web. 19 July 2013. [8] Wang, Jianxiong, Shi Zhou, Roger Bronks, John Graham, and Stephen Myers. "Supervised exercise training combined with ginkgo biloba treatment for patients with peripheral arterial disease." Clinical Rehabilitation . Web. 19 July 2013. [9] "RHODIOLA." WebMD.com. WebMD, n.d. Web. 19 July 2013. [10] "GINSENG, SIBERIAN." WebMD.com. WebMD, n.d. Web. 19 July 2013. [11] "COENZYME Q - 10." WebMD.com. WebMD, n.d. Web. 19 July 2013. [12] "GINKGO." WebMD.com. WebMD, n.d. Web. 19 July 2013.